C++ frameworks are great to develop new methods from other previously coded methods. Here are some great frameworks for medical imaging:
ITK Insight Segmentation and Registration Toolkit http://www.itk.org/
As the name states, it is great for segmentation and registration, but also has filters, statistics...
STIR Software for Tomographic Image Reconstruction http://stir.sourceforge.net/
It is a open-source framework to reconstruct data for nuclear medicine.
ROOT Rapid Object Oriented Data Framework http://root.cern.ch/
It is one of the major open source codes ever developed for Physics, so it is great to use in medical physics oriented medical imaging.
XIP eXtensible Imaging Platform http://www.openxip.org/
https://wiki.nci.nih.gov/display/XIP/eXtensible+Imaging+Platform+-+XIP
A platform design for rapid development of medical applications including DICOM tools, renders...
MITK Medical Imaging Toolkit http://www.mitk.org/
A framework which comprises ITK and VTK, a visualization toolkit.
A complete list with more frameworks:
http://www0.cs.ucl.ac.uk/opensource_mia_ws_2012/links.html
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